In addition, there are reports that MCP-1 can be elevated without significant increase in other cytokines such as Il-6 in various situations such as SARS CoV-2 infection of septic patients (Eichhorn et al. 2023) and chronic fatigue syndrome (Groven et al. 2020). This evidence concerns the gene CCL2 and myalgic encephalomeyelitis/chronic fatigue syndrome.