This migration of CTLs requires a tracking receptor switch from lymphoid tissue‐ (CD62L and CCR7) to effector site‐homing receptors (e.g., CXCR3, CCR8, CCR5, CCR2, and CCR1) upon antigen priming.[19] In this regard, we further examined the expression of CCR7 and CXCR3 (a major Teff‐associated chemokine receptor) by CTLs in the dLNs of tumor‐bearing control, RARα‐KO, and RARα‐TG mice (Figure 3A–C). This evidence concerns the gene CCR8 and neoplasm.