Through targeting signal transducer and activator of transcription 1 (STAT1)[40] and carcinoembryonic antigen‐related cell adhesion molecule 1 (CEACAM1),[41] miR‐31 has been found to blunt Th1 responses and enhance Treg cell differentiation, thereby exerting a protective effect during HIV infection and the progression of systemic lupus erythematosus. Here, CEACAM1 is linked to systemic lupus erythematosus.