Conversely, by suppressing SH2 domain containing 1A (SH2D1A)[42] and GPRC5A,[16] miR‐31 promotes Th1 cytokine transcription but suppresses Treg generation, thus promoting autoimmunity in sepsis and experimental autoimmune encephalomyelitis. The gene discussed is GPRC5A; the disease is experimental autoimmune encephalomyelitis.