In our study, we examined the linkage between autophagy and cell death in TRAF3IP3‐overexpressing LUAD cells and found that cancer cell death was promoted in cells slicing ATG7 or treated with autophagy inhibitor in those cells, indicating that autophagy contributes to the promotion of survival of TRAF3IP3‐overexpressing human lung cancer cells. This evidence concerns the gene TRAF3IP3 and lung cancer.