Clear associations between phenotypes and genetic subtypes (e.g., MCD with extranodal sites or EZB-MYC and high-grade B-cell lymphoma (HGBCL)/DLBCL with MYC and BCL2 double hits) suggest that these differences may be related to the inherent heterogeneity of DLBCL and the selection of cohorts. Here, MYC is linked to diffuse large B-cell lymphoma.