Clear associations between phenotypes and genetic subtypes (e.g., MCD with extranodal sites or EZB-MYC and high-grade B-cell lymphoma (HGBCL)/DLBCL with MYC and BCL2 double hits) suggest that these differences may be related to the inherent heterogeneity of DLBCL and the selection of cohorts. Here, BCL2 is linked to B-cell non-Hodgkin lymphoma.