ANO5 and gnathodiaphyseal dysplasia: Mutations in the ANO5 gene are associated with muscular or skeletal diseases, with recessive mutations manifesting as muscular disorders, commonly described as limb-girdle muscular dystrophy R12 and Miyoshi muscular dystrophy type 3, and dominant mutations presenting as skeletal disorders, notably gnathodiaphyseal dysplasia (GDD) (4).