Longitudinal kinetics analysis using fresh PBMCs derived from a separate MS patient cohort (Supplemental Table 1) revealed substantial decreases in the frequencies of these autoreactive CCR6+CXCR3+CD4+ T cells 6 months after treatment, whereas no significant changes were observed in CCR6+CXCR3+ cells in non-tetramer-reactive CD4+ T cells. Here, CCR6 is linked to myeloid sarcoma.