Body weightswere not significantly different between the control and PFOS-treatedmice (Figure 7B), andwhile relative tumor weights were increased in the 0.5 mg/kg/day treatmentgroup, the effect was not significantly different than the controlsor mice treated with 0.2 mg/kg/day PFOS (Figure 7C) due to interindividual animal variability.Results in Figure 7D show that in tumor lysates from the 0.5 mg/kg/day treatment grouplevels of NR4A1-responsive genes were significantly induced comparedto controls, and this further supports that PFOS is acting throughNR4A1. Here, NR4A1 is linked to neoplasm.