Very numerous atypical cells of variable morphology: part with sparse‐granular cytoplasm, round nuclei with nucleolies, other larger with more acidophilic cytoplasm with excentric nuclei and large degree of atypia. All (100%) atypic cells present positive MPO activity, some with slight CD33 positivity. In concordance with clinical data, the picture presents myeloid neoplasm infiltration, morphologically closest to promyelocytes/myelocytes. This evidence concerns the gene MPO and myeloid neoplasm.