The literature also reveals five NfL cleavage products in Alzheimer disease (Budelier et al. 2022), two NfL cleavage products in spinal cord injury (Shaw et al. 2023), one NfL cleavage product and two NfM cleavage products from human induced pluripotent stem cells (Nezvedová et al. 2023) (iPSCs), and five NfH cleavage products identified from microdialysis human brain interstitial fluid in traumatic brain injury (Petzold et al. 2011). The gene discussed is NEFL; the disease is early-onset autosomal dominant Alzheimer disease.