Similarly, mutations in PRPF8 have been implicated in the development of myeloid malignancies, like acute myeloid leukemia (AML) and myelodysplastic syndromes, by disrupting splicing in blood progenitor cells and promoting uncontrolled proliferation (Kurtovic‐Kozaric et al. 2015). The gene discussed is PRPF8; the disease is acute myeloid leukemia.