Current researches have highlighted the role of pro-inflammatory cytokines (IL-1β, IL-2, IL-6, IL-7, IL-8, IL-9, IL-10, IL-17, IL-18, IL-22, IL-33, TNF-α, IFN-γ, IFN-γ induced protein 10 (IP-10), monocyte chemoattractant protein-1 (MCP-1), and granulocyte-macrophage colony-stimulating factor (GM-CSF), chemokine (C-X-C motif) ligand (CXCL)10) in the severity of COVID-19 (11–15). This evidence concerns the gene IL1B and COVID-19.