AKT1 and neoplasm: Overall, AA exerted a significant impact on the proliferation of tumor cells, primarily through the upregulation of P53 and P21 protein expression, inhibition of the PI3K/AKT/mTOR/P70S6K signaling pathway, promotion of the p38 signaling pathway, and inhibition of ERK, along with other multiple pathways to induce cell cycle arrest, thereby inhibiting the growth and proliferation of tumors (Its specific mechanism of inhibiting the proliferation is shown in Figure 2).