Liu et al. (2023a) discovered that AA significantly increased the Bax/Bcl-2 ratio and expression of BCL-2-associated X protein (Bax), cleaved Caspase-3, cytochrome C (Cyt-C) in prostate cancer DU145 cells, while downregulating the Bcl-2 protein expression. This evidence concerns the gene CASP3 and Familial prostate cancer.