Their other study (Liu et al., 2023b) revealed that AA concentration-dependently increased the expression of Bax and cleaved Caspase-3 in prostate cancer PC-3 cells, downregulated the Bcl-2 expression of, facilitated the reduction of mitochondrial membrane potential leading to apoptosis of prostate cancer PC-3 cells, and could effectively inhibit the phosphorylation levels of JAK2 and STAT3 in the JAK2/STAT3 signaling pathway, thereby exerting an anti-prostate cancer effect. This evidence concerns the gene STAT3 and prostate carcinoma.