IL6 and pulmonary fibrosis: He et al. (He et al., 2015) found that Tan IIA reduces the expression levels of tumor necrosis factor-β (TNF-β), IL-1β, and IL-6 in the bronchoalveolar lavage fluid (BALF) of BLM-induced rats and also inhibits the expression of inducible nitric oxide synthase (iNOS) in lung tissue, thus reducing NO production and alleviating the inflammatory response in pulmonary fibrosis.