RHOA and asthma: Thrombin induces actin stress fiber polymerization via the protease‐activated receptor 1/RhoA/ROCK/myosin light chain 2 axis, activates YAP, and then interacts with mothers against decapentaplegic (SMAD)2 in the nucleus to trigger downstream target genes, ultimately fostering airway smooth muscle remodeling in asthma [78].