Thrombin induces the doublecortin like kinase 1/Ras homolog gene family, member A (RhoA) signaling pathway, activating YAP and forming YAP/p65, which enhances IL‐8/chemokine (C–X–C motif) ligand 8 (CXCL8) expression through NF‐κB binding, contributing to asthma development [55]. Here, CXCL8 is linked to asthma.