Contrary to results obtained in the middle-aged population (sensitivity 91.1% and specificity 71.4% for PTX-3 cutoff of 2.45 ng/mL) (14) and adolescents with obesity (sensitivity 89.0% and specificity 86.0% for PTX-3 cutoff of 3.03 ng/mL) (16). Here, PTX3 is linked to obesity due to melanocortin 4 receptor deficiency.