Therefore, to assess this relationship in a large cohort of older adults, participants from a population-based Polsenior 2 study were assessed for plasma pentraxin 3 (PTX-3) levels and their potential association with fibrosis diagnosis in metabolic dysfunction-associated steatohepatitis (MASH), based on the FIB-4 scores, NFSs, and HFSs. This evidence concerns the gene PTX3 and fibrosis.