VEGFA and neoplasm: A study demonstrated that vasoactive factors, such as vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF), along with the inflammatory cytokine interleukin-6 (IL-6), were significantly elevated in ascitic fluid compared to serum and pleural fluid, suggesting that tumor-secreted vasoactive factors increase peritoneal vascular permeability and lead to transudation and ascites formation (66).