This analysis explores the binding affinities of these ligands against key proteins involved in cancer pathways: Epidermal growth factor receptor (EGFR, PDB ID: 1XKK), aromatase (PDB ID: 3S7S), and Phosphoinositide 3-kinase alpha (PI3K alpha, PDB ID: 7PG6). The gene discussed is EGFR; the disease is cancer.