Additionally, L-glutaminase from Halomonas meridiana has demonstrated significant anticancer activity against colorectal cancer cells, with potent cytotoxic effects and IC50 values of 7.0 μg/mL for LS 174T cells and 13.2 μg/mL for HCT 116 cells, indicating its effectiveness in inhibiting tumor growth and promoting apoptosis [101]. The gene discussed is GLS2; the disease is neoplasm.