Geometric mean (SD range) plasma NT-proBNP concentrations in our 79 RTHβ participants were significantly lower than those of the 52 unselected patients with newly diagnosed conventional thyrotoxicosis [51 (18-142) vs 197 (73-530) pg/mL; P < .001] of similar age and sex distribution (mean ± SD age 41.7 ± 13.9 vs 38.5 ± 14.9 years, 28.8% vs 43.0 males; P ≥ .140). Here, NPPB is linked to thyrotoxicosis.