Intravitreal anti-VEGF injections are routinely being used to treat various ocular diseases such as diabetic macular edema, choroidal neovascularization associated with wet age-related macular degeneration, pathological myopia, retinopathy of prematurity and macular edema due to retinal vascular occlusions [3]. The gene discussed is VEGFA; the disease is retinal vein occlusion.