POMC and Adrenal insufficiency: As demonstrated in Table 1, the patient's adrenocorticotropic hormone (ACTH) and cortisol levels were significantly below the normal reference range, a key indicator of adrenal insufficiency. This finding, coupled with clinical symptoms, confirmed the diagnosis of pembrolizumab-induced AI. She was administered a physiological maintenance of hydrocortisone 15mg; her symptoms significantly improved the next day.