Numerous interactome studies in cancer cell lines report the interaction of SWI/SNF CRC subunits with TFs such as MYC [58, 100], SOX2 [101], SOX4 [100], TP53 [102], HOMEZ, HSFY1, IKZF3 [103], JUN [104], EPAS1 [105], ESR1 [106], ESR2 [107], RELB [108], and RXRA [103], although the data highlighting how this interaction may be involved in cancer development is missing. The gene discussed is IKZF3; the disease is cancer.