Anoctamin 1 (ANO1) can improve the recruitment of cancer-associated fibroblasts (CAFs) into TME by restraining tumor ferroptosis and promoting TGF\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\beta$$\end{document}β secretion, which is a potential mechanism of drug resistance [179, 192]. The gene discussed is ANO1; the disease is neoplasm.