Specific to Europeans (MAF = 1.0e-04), loss of DNAJC5 exon 4 supported by 13 read-pairs and with around 50% reduction in read depth (Supplementary Fig. 6 and Supplementary Table 10), was identified in a single European patient presenting for surgery at age 63 years with ISUP GG5 disease, yet appears to remain diploid during tumour development. This evidence concerns the gene DNAJC5 and neoplasm.