INS and type 2 diabetes mellitus: None of the variant groups was significantly associated with the glycaemic phenotypes or type 2 diabetes prevalence after correction for multiple testing (Fig. 2 and ESM Tables 6, 7), except for the common WT-like G24E variant displaying an elevated estimated insulin response (p=0.0032; ESM Fig. 3a, ESM Table 6) (after BMI adjustment, p=0.024).