Brain tumor angiogenesis, which is closely associated with brain tumor progression, is mediated through the action of many angiogenic factors including vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), hepatocyte growth factor (HGF), platelet-derived growth factor (PDGF), and TGF-β, MMPs, and angiopoietins (Angs) [4]. This evidence concerns the gene HGF and brain neoplasm.