In the GBM group, we noticed changes in several homeobox genes, e.g., NKX3-1, HOXA10, PROX1, EN2, DLX1 and HOXB3 (all FDR < 0.05 and at least fourfold deregulation), which were all upregulated in the samples from female patients. Here, EN2 is linked to glioblastoma.