Although the ligands of CXCR3—CXCL9, CXCL10, and CXCL11—are key ISGs (Groom and Luster, 2011a, 2011b; Marsman et al., 2018), it is unknown how blocking IFNAR during viral infection impacts chemokine expression for preferential formation of TSCM cells. This evidence concerns the gene CXCL10 and viral infectious disease.