In the study of pancreatic cancer microenvironment, the exploration of tumor‐associated neutrophils (TAN) heterogeneity has found subpopulations associated with poor prognosis, including terminally differentiated tumor‐promoting subpopulations (TAN‐1), inflammatory subpopulations (TAN‐2), transitional subpopulations newly migrated to the TME (TAN‐3), and subpopulations, that preferentially express interferon‐stimulated genes (TAN‐4) [130]. Here, STING1 is linked to neoplasm.