There were no pathogenic variants identified that were associated with immunodeficiency. He was a carrier for a single heterozygous pathogenic variant in Mediterranean fever (MEFV), which was consistent with carrier status for autosomal recessive familial MEFV. Several additional heterozygous variants of uncertain significance (VUS) were also noted, for which limited information is available. This evidence concerns the gene MEFV and immunodeficiency disease.