CD8A and neoplasm: Idecabtagene is comprised of a murine extracellular scFv of the C11D5.3 monoclonal antibody that binds to BCMA on tumor cells followed by a human CD8α hinge and transmembrane domain fused to the costimulatory molecule 4–1BB (CD137) and the T cell activation domain CD3ζ chain (14, 57).