In addition to the known fields, the critical role of IFIT3 in a variety of cancer types, including but not limited to esophageal squamous cell carcinoma (45, 65), myeloma, leukemia (73, 74), breast cancer (66), nasopharyngeal carcinoma (80), bladder carcinoma (69), thyroid carcinoma (72), and melanoma (70), has been further revealed utilizing comprehensive bioinformatic analyses and other means. This evidence concerns the gene IFIT3 and cancer.