SOX4 and lung cancer: Its overexpression also induces pulmonary fibrosis by interfering with the circHIPK3/miR-30a-3p/FOXK2 axis (108) and by inducing fibroblast-to-myofibroblast transition via regulation of circHIPK3/miR-338-3p/SOX4/COLA1A1 (109), this condition is a factor in risk for lung cancer (110).