circHIPK3 contains multiple sites for the same RBPs (e.g., DDX54, EIF4A3, FMR1, IGF2BP1, IGF2BP2, LIN28B and MOV10), many of which are involved in chemoresistance and organelle-like structures, such as Cajal body and P-body which are associated with cancer. Here, FMR1 is linked to cancer.