The NTRK family, which includes NTRK1, NTRK2, and NTRK3 genes, encodes these Trk receptors and their respective ligands, affecting key signalling pathways involved in cancer progression (Hondermarck 2012, Tajbakhsh et al. 2017, Saroğlu et al. 2024). The gene discussed is NTRK2; the disease is cancer.