Although not the focus of this study, we observed that being female is associated with greater GFAP levels in both dementia and non-dementia groups and the difference is greater in the dementia group (Beta = 0.27, CI: 0.20 – 0.34, P = 5.4E-14) than in the non-dementia group (Beta = 0.15, CI: 0.14 – 0.16, P = 2.2E-192) (Supplementary Table 3a and 3b). The gene discussed is GFAP; the disease is dementia.