Indeed, we found increased expression of the chemokine CXCL12 by FRCs in a DLBCL transwell migration assay, indicating that this chemokine may play a role in DLBCL attraction and migration by FRCs, but the molecular mechanism and factors driving DLBCL dissemination remain to be further investigated. This evidence concerns the gene CXCL12 and diffuse large B-cell lymphoma.