Ag testing averted 0.027% of infections, with mean QALYs increasing by 0.0009 (95% credible range=0.0001, 0.0023), at an incremental net cost of $97 ($76, $119) and $8 (−$171, $129) per shelter resident from the healthcare payer and societal perspectives, respectively. This evidence concerns the gene RENBP and infection.