MICA and neoplasm: For instance, the NKG2D receptor, belonging to the killer lectin-like receptor family, recognizes ligands which are frequently expressed on tumour cells undergoing oncogenic stress, such as major histocompatibility complex (MHC) class I chain-related protein A (MIC-A) and MHC class I chain-related protein B (MIC-B) and UL16-bindingproteins (ULBPs) [1, 2].