Six infertile men presented a history of cancerous or non-cancerous tumors—leiomyosarcoma (BRCA2 p.Ser599Ter), lymphoma (TP53 p.Arg181His), basalioma (WT1 p.Trp151Gly), fibroma and renal cysts (TSC1 p.Ala428fs), neoplasms of uncertain behavior (PHOX2B p.Phe33fs), and schwannomatosis (LZTR1 p.Arg283Gln) (Table 2). This evidence concerns the gene LZTR1 and cystic kidney disease.