Six infertile men presented a history of cancerous or non-cancerous tumors—leiomyosarcoma (BRCA2 p.Ser599Ter), lymphoma (TP53 p.Arg181His), basalioma (WT1 p.Trp151Gly), fibroma and renal cysts (TSC1 p.Ala428fs), neoplasms of uncertain behavior (PHOX2B p.Phe33fs), and schwannomatosis (LZTR1 p.Arg283Gln) (Table 2). Here, TSC1 is linked to fibroma.