On most occasions, the reported tumor types matched the patient’s genetic findings, e.g. early-onset breast (family history of patients with findings in BRCA1, BRCA2, BRIP1, NF1), prostate (BRCA2, FANCM, TP53, WT1), renal (TSC1), gynecological (BRIP1, TSC1), and hematological cancers (MLH1, TP53, WT1). The gene discussed is TSC1; the disease is hematopoietic and lymphoid cell neoplasm.