CD24 and urinary bladder carcinoma: In breast cancer celllines, MCF-7 decreased the proliferation of tumorspheres while increasingthe expression of CD24 by suppression of the Gli1/Hh pathway.58 Additionally, studies on bladder cancer revealedthat solasodine (24) can suppress NRP1 expression andlead to a proapoptotic and antiproliferative effect,59 showing a different death pathway than those observed insaponins and phytosterols, particularly because they act at the geneticlevel by changing CD24 expression to favor apoptotic death processes.