In breast cancer models, some studies have reportedthat diosgenininfluences several signaling pathways crucial to the progression ofbreast cancer, including FoxO, PI3K-Akt, p53, Ras, and MAPK signaling.This could potentially result in the deceleration of cell growth,contrary to the Warburg phenomenon, and the induction of cytotoxiceffects on breast cancer cells.19 The gene discussed is TP53; the disease is breast cancer.