Several in vitro and in vivo studies have shown significant inhibition of non-small-cell lungcancer proliferation, survival, migration, and angiogenesis by inhibitingKIF11-CDK1-CDC25C-cyclin B1 and the κNF-B pathway,64 confirming that steroids have direct potentialon lung cancer cell lines, focusing on apoptotic pathways. The gene discussed is CDK1; the disease is lung carcinoma.