Supplemental Table 1 shows clinical characteristics. Median XPC mRNA expression was decreased in human lung adenocarcinoma compared to non-cancerous, resected lung from the same individual (Figure 7 B and C). The ratio of XPC mRNA expression was decreased in lung adenocarcinoma tissue compared to subject-matched benign lung irrespective of cigarette smoking status and stage at the time of diagnosis (Supplemental Figure 2 and Figure 7C). Here, XPC is linked to lung adenocarcinoma.