In glioma, PDGFB and its cognate receptor, PDGFRA, are detected in mIDH tumors (Fig. S1c), whereas, in the non-tumor human brain, PDGFB is minimally expressed by microglia and vascular cells, and PDGFRA is highly expressed by OPCs (Figs. S1d). This evidence concerns the gene PDGFB and central nervous system cancer.