Specifically, OIP5‐AS1 promotes ubiquitination and degradation of the transcription factor sterol regulatory element‐binding protein 1 (SREBP1), inhibiting hexokinase domain containing 1 (HKDC1) transcriptional activity, blocking glycolysis in liver cancer cells, and ultimately restraining tumor progression [262]. The gene discussed is HKDC1; the disease is neoplasm.