Microarray analysis has shown that HCV infection significantly upregulates genes related to inflammation and angiogenesis, including amphiregulin (AREG), IL‐8, and C‐C motif chemokine ligand 20 (CCL20), which accelerate HCC progression by promoting inflammation and angiogenesis in the tumor microenvironment [432]. The gene discussed is CXCL8; the disease is neoplasm.