ARID3B and colorectal carcinoma: ARID3B is mainly involved in determining CRC development and progression around immune escape and stem cell properties, and overexpression of ARID3B facilitates the recruitment of lysine demethylase 4C to the regulatory regions of NOTCH target genes and intestinal stem cell genes, thereby promoting the transcriptional activation of stem cell‐associated target genes through the demethylation of H3K9me3 [55].