Serum biomarkers such as procalcitonin (PCT), C-reactive protein (CRP), TNF-related apoptosis inducing ligand (TRAIL) and Interleukin-10 have shown limited success as a supplement to clinical judgment in assessing patients with ARI, and currently biomarker testing is not routinely recommended for management of respiratory infections.33,34. The gene discussed is TNFSF10; the disease is respiratory tract infectious disorder.