To date, nearly 200 deafness-related loci and causative genes within these loci have been identified (https://hereditaryhearingloss.org/); by far the most common and best-characterized gene is gap junction β2 (GJB2; OMIM 121011), which encodes connexin 26 (CX26) (5). Here, GJB2 is linked to deafness.