The results revealed no measurable leakage of the encapsulated albumin, and most of the albumin accumulated in the liver.175 Since then, liposomes have been widely used as drug delivery systems.176–178 Yano et al. complexed siRNA-B717, which targets the human Bcl-2 oncogene, with a novel cationic liposome, LIC-101, containing 2-O-(2-diethylaminoethyl)-carbamoyl-1,3-O-dioleoylglycerol and egg phosphatidylcholine and intravenously injected into mice with liver metastasis and subcutaneously injected into prostate cancer-bearing mice (inoculated under the skin). The gene discussed is ALB; the disease is prostate cancer.