REN and escherichia coli infection: The 18 common pathways were pathogenic Escherichia coli infection, rheumatoid arthritis, arachidonic acid metabolism, Fc gamma R-mediated phagocytosis, oxytocin signaling pathway, GnRH signaling pathway, the C-type lectin receptor signaling pathway, serotonergic synapses, thermogenesis, the regulation of lipolysis in adipocytes, renin secretion, the peroxisome proliferator-activated receptor (PPAR) signaling pathway, bile secretion, inflammatory mediator regulation of TRP channels, circadian entrainment, vitamin digestion and absorption, fat digestion and absorption, and taste transduction.