MAPK8 and Duchenne muscular dystrophy: Interestingly, the gProfiler analysis also revealed that signaling pathways attributed to skeletal muscle stem cell function37 were differentially enriched in DMD MPCs, such as p38 mitogen-activated protein kinase (MAPK) signaling,38,39 Jun N-terminal kinase (JNK) signaling,40 Wnt signaling,41 notch signaling,42 and regulation of mitotic spindle/cell cycle.43